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Omniscient Neurotechnology conducts independent and collaborative research with institutions around the world. We provide insight into neuropathology through advanced brain mapping and connectomic analyses.
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Displaying 1-9 of a total 98 articles.
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Quicktome's connectomic analysis on brain malformation surgery exposed 7 unforeseen eloquent regions, highlighting the need for refined surgical strategies and a broader definition of cortical...
Despite advances in surgical treatments for brain tumors improving survival, connectomics enables a nuanced focus on preserving patients' neurocognitive functions and life reintegration.
Neurosurgeons incorporated connectomes into radiosurgical planning, enabling safer dose delivery by protecting crucial brain networks in a patient's AVM treatment.
Comparison of the pre- and postoperative connectome can be used to objectively evaluate surgical outcomes and assess patient prognosis. To the best of the authors’ knowledge, this is the first case...
Using machine learning, individual brain connectivity analyses reveal unique recovery paths in stroke patients post-treatment.
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Quicktome revealed functional regions at risk of damage during resection, and it correlated to intraoperative language mapping findings.
Analysed anomaly patterns in anxiety patients, revealing that the default mode network (DMN) is likely the primary network disturbed in anxiety-related disorders.
Found the SCA to be a viable option for pre-surgical planning and general clinical use.
We mapped the visual network and found interesting insights on its role in non-visual connections.
Conducted in collaboration with Shanghai Mental Health Centre, we modelled the anatomical circuits underlying schizophrenia symptoms.
Joint study with Monash University compares functional connectivity patterns in TMS responders vs non-responders for MDD treatment. Machine learning identified potential treatment targets.
Demonstrates how connectomics can be a valuable asset in stroke management when used in predictive modelling of neuro-rehabilitation outcomes.
The correspondence describes a novel scale (the "Sughrue-Ivan" scale) to describe a tumour's location and risk relative to large-scale brain networks.
Through graphically representing the brain, mathematical graph theory approaches may be able to provide additional information on important inter-individual network properties and functionally...
Meta-analysis of functional connectivity in MDD suggests abnormal interactions between brain networks, particularly increased default mode-central executive pairs and decreased default mode-other...
A retrospective analysis of 100 brain tumor surgery patients using Quicktome. Quicktome showed the extensive involvement of non-traditional networks around regions of pathology that would not...
A high powered prospective study comparing healthy individuals and insomnia patients revealed Connectomic changes in the DMN and associated networks underlying the severity of the disorder.
This retrospective investigation of 95 patients operated on between 2012-2017 advocates for the safety of keyhole approaches for removal of giant intracranial tumors.
Gerstmann syndrome is a neurological phenomena associated with a variety of motor and cognitive deficits. From a large clinical dataset, we identify brain networks compromised in this syndrome.
A case review demonstrating the utility of o8t software alongside neurorehabilitation to assess functional recovery after glioma removal.
The Hollow Tree Super (HoTS) method was applied to a patient and healthy control group to define parcels and networks corresponding with diagnosis of MCI and Alzheimers.
A review of the current applications of Machine Learning and AI in health science data, and how users can avoid common mistakes when handling data.
A report on single-center experience using Quicktome for resection of intra-axial brain tumors
A meta-analytic approach revealing the cognitive and emotional consequences of damaging brain networks in neurosurgery.
A retrospective assessment of the recent progression in clinical utility of Transcranial Magnetic Stimulation (TMS). The end goal of a patient-specific application is discussed.
A formal investigation of the prevalence of co-morbid mental health disorders following Glioma diagnosis between 2005-2014
A proof-of-concept study demonstrating the capability of o8t software in generating personalized TMS targets for post-craniotomy neurorehabilitation
An investigation of two graph theory metrics: Eigenvector and PageRank centrality, and how they together inform unique and neurosurgically meaningful topological characteristics of the brain
A retrospective investigation using Quicktome to demonstrate brain networks compromised by Glioma.
As the basis for the creation of our patient-specific brain maps, this manuscript unveils the Structural Connectivity Atlas (SCA) methodology
As the basis for the creation of our patient-specific brain maps, this manuscript unveils the Structural Connectivity Atlas (SCA) methodology
In this case report, we use Infinitome to find optimal targets for rTMS in a patient who had suffered an Ischemic Stroke.
The Precuneus is involved in visuospatial processing and cognition. We reveal the major connections and functions of the precuneus.
This paper conceptualizes modern neurosurgical approaches from eloquence to centrality. We break down the major breakthroughs in the field which may benefit patient onco-functional balance.
Using Quicktome, our team re-examined cases of intracerebral surgery and demonstrated a machine-learning approach to investigating the organization of compromised brain networks.
Using Quicktome, our team re-examined cases of intracerebral surgery and demonstrated a machine-learning approach to investigating the organization of compromised brain networks.
A meta-analysis revealing the network constitutents of ideomotor apraxia. We present a connectivity model to explain the determinants of this condition.
A meta-analysis revealing the network constitutents of ideomotor apraxia. We present a connectivity model to explain the determinants of this condition.
The medial occipital lobe, composed of the lingual gyrus and cuneus, is necessary for basic and higher level visual processing. We investigate the connections of the medial occipital lobe.
Hollow-tree Super: a directional and scalable approach for feature importance in boosted tree models
This manuscript unveils a novel method for investigating which brain regions are most responsible for greater scores on psychometric tests such as the PANSS for Schizophrenia - Hollow Tree Super.
A case study highlighting the benefits of transcranial magnetic stimulation for restoring network functional connectivity in the DMN.
A re-opened investigation utilizing o8t atlassing revealed that inaccurate targeting of the dlPFC in veterans reduced treatment response.
The superior parietal lobule (SPL) is involved in somatosensory and visuospatial integration. We reveal the cortical constituents and connections of the SPL.
The Middle Frontal Gyrus (MFG) is involved in attention processing and working memory. We reveal the major connections and functions of the MFG.
The Ventral Premotor Area (VPM) is involved in motor control and execution. We reveal the major connections and functions of the VPM.
This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.
This study provides a retrospective investigation of the utility of Diffusion Tensor Imaging (DTI) for neurosurgical planning of medial frontal gliomas.
The middle temporal gyrus (MTG) is understood to play a role in language related tasks. We investigate the cortical connections and components of the MTG.
The supplementary motor area (SMA) plays a role in the initiation of internally and externally cued movements. This manuscript investigates the cortical connections of the SMA.
The Parahippocampal Gyrus (PHG) is involved in memory encoding and cognition. We reveal the major connections and functions of the PHG.
This dual case study reports on the use of theta burst stimulation (cTBS) for postoperative strategy following brain tumor resection.
By utilizing the o8t Infinitome processing pipeline, this study revealed connectomic anomalies in the Default Mode Network (DMN) which underpinned the progression of Alzheimer's Disease.
The default mode network (DMN) is an important mediator of passive states of mind. We investigate the cortical areas which constitute the DMN.
By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.
By utilizing PageRank Centrality, a common algorithm for search engine optimization, we investigated the remapping of neural hubs in individuals suffering from Schizophrenia.
Many cortical areas co-ordinate human's auditory sense. We present a tractographic model of the brain's primary auditory network
We present a surgical case study outlining a surgical anomaly: where resection of a tumor in the posterior middle frontal gyrus resulted in pure speech apraxia.
The fusiform gyrus is understood to be involved in the processing of high-order visual information. We characterize its connections by anatomical dissection and fibre tractography.
Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.
Connectomic approaches have bolstered surgical understanding of the brains major language networks. This manuscript summarizes and reviews these major advancements.
This manuscript investigates the cortical connections of the Dorsal Premotor Area (DPM), a critical region for coordinating hand muscle recruitment for motor tasks such as grasping and lifting.
In this study we explore whether centrality metrics can be utilized to inform the location of surgically eloquent regions. We found PageRank centrality reliably predicted surgically eloquent.
In this study we explore whether centrality metrics can be utilized to inform the location of surgically eloquent regions. We found PageRank centrality reliably predicted surgically eloquent.
By corroborating tractographic mapping with gross anatomic dissection, we characterize fiber tracts of the Superior Frontal Gyrus (SFG) based on their relationships to known neuroanatomic structures.
The lateral occipital lobe plays a role in object recognition, facial recognition, and motion perception. This manuscript investigates the cortical connections of the lateral occipital lobe.
The ventral attention network (VAN) is an important mediator of stimulus-driven attention. We investigate the cortical areas which constitute the VAN.
This manuscript presents a case report, treatment strategy, and subsequent outcomes of a patient suffering a rare bilateral carotid-cavernous fistula (CCF).
This study explores the use common graph theory metrics for defining functionally important areas of the cortex. Those we identified heavily overlapped with those known to be surgically eloquent.
The dorsal attention network (DAN) is an important mediator of goal‐ directed attentional processing. We investigate the cortical areas which constitute the DAN.
By corroborating tractographic mapping with gross anatomic dissection, we characterize fiber tracts of the Inferior Frontal Gyrus (IFG) based on their relationships to known neuroanatomic structures.
As part of a larger book on surgical management, this chapter discusses the functional organization of brain networks.
As part of a larger book on surgical management, this chapter discusses the functional organization of brain networks.
We present a novel hypothesis for the manifestation of Supplementary Motor Area (SMA) syndrome: that damaging the crossed frontal aslant tract subsists this neurosurgical consequence.
We present a novel hypothesis for the manifestation of Supplementary Motor Area (SMA) syndrome: that damaging the crossed frontal aslant tract subsists this neurosurgical consequence.
This manuscript offers expert advice on neurosurgical approaches for glioma removal in the cortex, including how best to preserve eloquent brain regions and their connections.
The orbitofrontal cortex (OFC) is understood to have a role in outcome evaluation and risk assessment. We characterize the connections of the OFC by anatomical dissection and fibre tractography.
By corroborating tractographic mapping with anatomic dissection, we characterize fiber tracts of the Inferior Parietal Lobule (IPL) based on their relationships to known neuroanatomic structures.
By corroborating tractographic mapping with anatomic dissection, we characterize fiber tracts of the Inferior Parietal Lobule (IPL) based on their relationships to known neuroanatomic structures.
By assessing the operative results of 43 craniotomy patients, we report on the use and benefit of DTI implementation in surgical workflows.
By assessing the operative results of 43 craniotomy patients, we report on the use and benefit of DTI implementation in surgical workflows.